A bombing at Cairo’s largest Coptic cathedral killed at least 25 people and wounded 49, many of them women and children attending Sunday mass, in the deadliest attack on Egypt’s Christian minority in years.

The attack comes as President Abdel Fattah al-Sisi fights battles on several fronts. His economic reforms have angered the poor, a bloody crackdown on the Muslim Brotherhood has seen thousands jailed, whilst an insurgency rages in Northern Sinai, led by the Egyptian branch of Islamic State.

The militant group has also carried out deadly attacks in Cairo and has urged its supporters to launch attacks around the world in recent weeks as it goes on the defensive in its Iraqi and Syrian strongholds.

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